Last position-specific scoring matrix computed, weighted observed percentages rounded down, information per position, and relative weight of gapless real matches to pseudocounts A R N D C Q E G H I L K M F P S T W Y V A R N D C Q E G H I L K M F P S T W Y V 1 M -1 -1 -2 -3 -1 0 -2 -3 -1 1 2 -1 5 0 -2 -1 -1 -1 -1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.00 0.00 2 A 5 -2 -2 -2 -1 -1 -1 0 -2 -2 -2 -1 -1 -3 -1 1 0 -3 -2 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.55 0.10 3 R -2 6 -1 -2 -4 1 0 -3 -1 -3 -3 2 -2 -3 -2 -1 -1 -3 -2 -3 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.93 0.10 4 R -2 6 -1 -2 -4 1 0 -3 -1 -3 -3 2 -2 -3 -2 -1 -1 -3 -2 -3 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.93 0.10 5 K -1 2 0 -1 -3 1 0 -2 -1 -3 -3 5 -2 -3 -1 0 1 -3 -2 -2 0 0 0 0 0 4 0 0 0 0 0 82 0 0 0 0 14 0 0 0 0.55 0.11 6 R -2 6 -1 -2 -4 1 0 -3 -1 -3 -3 2 -2 -3 -3 -1 -1 -3 -2 -3 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.94 0.11 7 R -2 6 -1 -2 -4 1 0 -3 -1 -3 -3 3 -2 -3 -2 -1 -1 -3 -2 -3 0 86 0 0 0 0 0 0 0 0 0 14 0 0 0 0 0 0 0 0 0.86 0.11 8 N -2 -1 6 1 -3 0 -1 -1 2 -4 -4 -1 -3 -3 -2 0 0 -4 -2 -3 0 0 95 0 0 0 0 0 5 0 0 0 0 0 0 0 0 0 0 0 0.89 0.11 9 F -3 -3 -3 -4 -3 -3 -4 -4 -2 0 0 -3 1 7 -4 -3 -2 1 3 -1 0 0 0 0 0 0 0 0 0 0 0 0 5 95 0 0 0 0 0 0 0.92 0.11 10 N 0 -1 3 0 -2 0 -1 -1 -1 -3 -3 -1 -2 -3 -1 4 1 -3 -2 -2 0 0 24 0 0 0 0 0 0 0 0 0 0 0 0 76 0 0 0 0 0.54 0.11 11 K -1 3 -1 -1 -4 1 0 -2 -1 -3 -3 5 -2 -3 -2 -1 -1 -3 -2 -3 0 18 0 0 0 0 0 0 0 0 0 82 0 0 0 0 0 0 0 0 0.67 0.11 12 Q -1 0 0 -1 -3 6 2 -2 0 -3 -2 1 -1 -3 -2 0 1 -2 -2 -2 0 0 0 0 0 84 4 0 0 0 0 0 0 0 0 0 12 0 0 0 0.70 0.11 13 A 4 -2 -1 -2 -1 -1 -1 0 -2 -2 -2 -1 -1 -3 -1 2 0 -3 -2 -1 74 0 0 0 0 0 0 0 0 0 0 0 0 0 0 26 0 0 0 0 0.47 0.11 14 T 0 -1 0 -1 -1 -1 -1 -2 -2 -1 -2 -1 -1 -3 -1 2 5 -3 -2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7 93 0 0 0 0.62 0.11 15 E -1 0 -1 1 -4 2 6 -3 0 -4 -3 0 -2 -4 -1 0 -1 -3 -2 -3 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0.90 0.11 16 I -1 -3 -4 -4 -1 -3 -3 -4 -4 4 1 -3 1 -1 -3 -2 -1 -3 -2 4 0 0 0 0 0 0 0 0 0 60 0 0 0 0 0 0 0 0 0 40 0.50 0.11 17 L -2 -3 -4 -4 -2 -3 -3 -4 -3 1 5 -3 2 0 -3 -3 -2 -2 -1 1 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0.62 0.11 18 N -2 -1 6 1 -3 0 -1 -1 0 -4 -4 0 -3 -3 -2 0 0 -4 -2 -3 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.93 0.11 19 E -1 0 2 1 -4 1 5 -2 0 -4 -3 0 -2 -4 -2 0 -1 -3 -2 -3 0 0 13 0 0 0 87 0 0 0 0 0 0 0 0 0 0 0 0 0 0.78 0.11 20 Y -2 -2 -3 -4 -3 -2 -2 -3 1 -2 -1 -2 -1 3 -3 -2 -2 2 7 -2 0 0 0 0 0 0 0 0 0 0 0 0 0 4 0 0 0 0 96 0 1.07 0.11 21 F -3 -3 -3 -4 -3 -4 -4 -4 -2 0 0 -4 0 7 -4 -3 -3 1 3 -1 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0.98 0.11 22 Y -2 -2 -2 -3 -3 1 -2 -3 1 -1 0 -2 -1 2 -3 -2 -2 1 7 -1 0 0 0 0 0 13 0 0 0 0 13 0 0 0 0 0 0 0 74 0 0.71 0.11 23 S 2 -1 0 -1 -1 -1 -1 1 -1 -3 -3 -1 -2 -3 -1 4 1 -3 -2 -2 26 0 0 0 0 0 0 5 0 0 0 0 0 0 0 69 0 0 0 0 0.46 0.11 24 H -2 -1 2 -1 -3 0 0 -2 8 -4 -3 -1 -2 -2 -3 -1 -2 -3 1 -4 0 0 13 0 0 0 0 0 87 0 0 0 0 0 0 0 0 0 0 0 1.00 0.11 25 L -2 -3 -4 -4 -2 -3 -3 -4 -3 3 4 -3 2 0 -3 -3 -1 -2 -1 1 0 0 0 0 0 0 0 0 0 26 74 0 0 0 0 0 0 0 0 0 0.53 0.11 26 S 1 -1 3 0 -1 0 -1 -1 -1 -3 -3 -1 -2 -3 -1 4 2 -3 -2 -2 3 0 19 0 0 0 0 0 0 0 0 0 0 0 0 64 13 0 0 0 0.47 0.11 27 N -2 -1 6 1 -3 0 -1 -1 5 -4 -4 -1 -2 -3 -2 0 -1 -4 -1 -3 0 0 74 0 0 0 0 0 26 0 0 0 0 0 0 0 0 0 0 0 0.77 0.11 28 P -1 -3 -2 -2 -3 -2 -1 -3 -3 -3 -3 -1 -3 -4 8 -1 -1 -4 -3 -3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 2.17 0.11 29 Y -2 -2 -2 -4 -3 -2 -2 -3 1 -2 -1 -2 -1 3 -3 -2 -2 2 7 -2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 1.10 0.11 30 P -1 -3 -2 -2 -3 -2 -1 -3 -3 -3 -3 -1 -3 -4 8 -1 -1 -4 -3 -3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 2.17 0.11 31 S 1 -1 0 -1 -1 0 -1 -1 -1 -2 -3 -1 -2 -3 -1 4 2 -3 -2 -2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 87 13 0 0 0 0.55 0.11 32 E -1 0 -1 1 -4 2 6 -3 0 -4 -3 0 -2 -4 -1 0 -1 -3 -2 -3 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0.90 0.11 33 E -1 0 -1 1 -4 3 5 -2 0 -4 -3 1 -2 -4 -2 0 -1 -3 -2 -3 0 0 0 0 0 13 87 0 0 0 0 0 0 0 0 0 0 0 0 0 0.82 0.11 34 A 4 -2 -2 -1 -1 -1 1 -1 -2 -1 -2 -1 -1 -3 -1 0 0 -3 -2 1 70 0 0 0 0 0 13 0 0 0 0 0 0 0 0 0 4 0 0 13 0.34 0.11 35 K -1 2 0 -1 -3 1 0 -2 -1 -3 -3 5 -2 -4 -1 -1 -1 -3 -2 -3 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0.69 0.11 36 E -1 0 -1 1 -4 3 5 -2 0 -4 -3 1 -2 -4 -2 0 -1 -3 -2 -3 0 0 0 0 0 13 87 0 0 0 0 0 0 0 0 0 0 0 0 0 0.83 0.11 37 E 1 -1 -1 2 -3 1 5 -2 -1 -3 -3 0 -2 -4 -1 0 -1 -3 -2 -2 13 0 0 5 0 0 82 0 0 0 0 0 0 0 0 0 0 0 0 0 0.70 0.11 38 L -2 -3 -4 -4 -2 -3 -3 -4 -3 1 5 -3 2 0 -3 -3 -2 -2 -1 1 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0.62 0.11 39 A 5 -2 -2 -2 -1 -1 -1 0 -2 -2 -2 -1 -1 -3 -1 1 0 -3 -2 -1 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.56 0.11 40 K -1 4 -1 -2 -3 1 0 -2 -1 -2 -2 4 2 -3 -2 -1 -1 -3 -2 -2 0 41 0 0 0 0 0 0 0 0 0 46 13 0 0 0 0 0 0 0 0.54 0.11 41 K -1 2 0 -1 -3 4 1 -2 -1 -3 -3 4 -1 -4 -1 0 -1 -3 -2 -3 0 0 0 0 0 35 0 0 0 0 0 65 0 0 0 0 0 0 0 0 0.61 0.11 42 S -1 -4 -2 -3 9 -3 -4 1 -3 -2 -2 -3 -2 -3 -3 -1 -1 -3 -3 -1 0 0 0 0 83 0 0 13 0 0 0 0 0 0 0 4 0 0 0 0 1.19 0.11 43 G 0 -2 4 0 -3 -1 -2 5 -1 -4 -4 -1 -3 -3 -2 1 -1 -3 -3 -3 0 0 31 0 0 0 0 56 0 0 0 0 0 0 0 12 0 0 0 0 0.70 0.11 44 I -2 -3 -4 -4 -2 -3 -4 -4 -4 5 2 -3 1 0 -3 -3 -1 -3 -2 2 0 0 0 0 0 0 0 0 0 94 6 0 0 0 0 0 0 0 0 0 0.56 0.11 45 T 0 -1 0 -1 -1 -1 -1 -2 -2 -1 -2 -1 -1 -3 -1 3 5 -3 -2 -1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 26 74 0 0 0 0.54 0.11 46 V -1 -3 -3 -4 -1 -3 -3 -4 -4 3 1 -3 0 -1 -3 -2 0 -3 -2 5 0 0 0 0 0 0 0 0 0 6 0 0 0 0 0 0 0 0 0 94 0.51 0.11 47 S 2 -1 0 -1 -1 -1 -1 2 -1 -3 -3 -1 -2 -3 -1 4 1 -3 -2 -2 16 0 0 0 0 0 0 13 0 0 0 0 0 0 0 71 0 0 0 0 0.47 0.11 48 Q -1 1 0 -1 -3 6 2 -2 0 -3 -3 1 -1 -4 -2 0 -1 -2 -2 -3 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.85 0.11 49 V 0 -3 -3 -3 -1 -2 -3 -3 -3 2 0 -2 0 -1 -3 -2 1 -3 -2 5 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9 0 0 91 0.45 0.11 50 S 1 -1 0 0 -1 0 1 -1 -1 -3 -3 0 -2 -3 -1 5 1 -3 -2 -2 0 0 0 0 0 0 9 0 0 0 0 0 0 0 0 91 0 0 0 0 0.55 0.11 51 N -2 -1 6 1 -3 0 -1 -1 0 -3 -4 -1 -2 -3 -2 0 1 -4 -2 -3 0 0 91 0 0 0 0 0 0 0 0 0 0 0 0 0 9 0 0 0 0.82 0.11 52 W -3 -1 -4 -4 -3 -2 -3 -3 -2 -3 -2 -3 -2 1 -4 -3 -3 11 3 -3 0 6 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 85 9 0 2.14 0.11 53 F -3 -3 -3 -4 -3 -4 -4 -4 -2 0 0 -4 0 7 -4 -3 -3 1 3 -1 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0.97 0.11 54 G 0 -3 -1 -2 -3 -2 -3 6 -2 -4 -4 -2 -3 -4 -3 -1 -2 -3 -3 -4 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 1.21 0.11 55 N -2 -1 6 1 -3 0 1 -1 0 -4 -4 0 -3 -3 -2 0 0 -4 -2 -3 0 0 91 0 0 0 9 0 0 0 0 0 0 0 0 0 0 0 0 0 0.84 0.11 56 K -1 3 -1 -1 -4 1 0 -2 -1 -3 -3 5 -2 -4 -1 -1 -1 -3 -2 -3 0 9 0 0 0 0 0 0 0 0 0 91 0 0 0 0 0 0 0 0 0.67 0.11 57 R -2 6 -1 -2 -4 1 0 -3 -1 -3 -3 2 -2 -3 -2 -1 -1 -3 -2 -3 0 94 0 0 0 0 0 0 0 0 0 6 0 0 0 0 0 0 0 0 0.90 0.11 58 I -2 -3 -4 -4 -2 -3 -4 -4 -4 5 1 -3 1 0 -3 -3 -1 -3 -2 2 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0.54 0.09 59 R -2 6 -1 -2 -4 1 0 -3 -1 -3 -3 2 -2 -3 -2 -1 -1 -3 -2 -3 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.91 0.09 60 Y -2 -2 -2 -3 -3 -2 -2 -3 1 -2 -1 -2 -1 3 -3 -2 -2 2 7 -2 0 0 0 0 0 0 0 0 0 0 0 0 0 4 0 0 0 0 96 0 1.03 0.09 61 K -1 2 0 -1 -3 1 1 -2 -1 -3 -3 5 -2 -3 -1 0 -1 -3 -2 -3 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0.66 0.09 62 K -1 2 0 -1 -3 1 1 -2 -1 -3 -3 5 -2 -3 -1 0 -1 -3 -2 -3 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0.66 0.09 63 N -2 -1 6 1 -3 0 -1 -1 0 -2 -2 -1 1 -3 -2 0 1 -4 -2 -2 0 0 78 0 0 0 0 0 0 0 0 0 11 0 0 0 11 0 0 0 0.60 0.09 64 I -1 -3 -3 -3 -2 -2 -3 -4 -3 4 2 -3 4 0 -3 -2 0 -2 -2 2 0 0 0 0 0 0 0 0 0 58 12 0 26 0 0 0 5 0 0 0 0.39 0.09 65 G 2 -2 -1 -2 -2 -2 -2 5 -2 -3 -3 -2 -2 -3 -2 1 -1 -3 -3 -1 17 0 0 0 0 0 0 66 0 0 0 0 0 0 0 13 0 0 0 4 0.69 0.10 66 K -1 2 0 -1 -3 1 1 -2 -1 -3 -3 5 -2 -4 -1 -1 -1 -3 -2 -3 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0.69 0.10 67 F 1 -2 1 -1 -2 -1 1 -2 -1 -1 -1 -2 -1 5 -3 -1 -2 0 2 -1 19 0 12 0 0 0 13 0 0 0 0 0 0 53 0 0 0 0 4 0 0.35 0.10 68 Q -1 1 0 0 -3 6 2 -2 0 -3 -3 2 -1 -4 -2 0 -1 -3 -2 -3 0 0 0 0 0 75 12 0 0 0 0 13 0 0 0 0 0 0 0 0 0.70 0.10 69 E -1 -1 0 2 -4 1 5 -2 -1 -4 -3 0 -2 -4 -1 1 -1 -3 -2 -3 0 0 0 12 0 0 75 0 0 0 0 0 0 0 0 13 0 0 0 0 0.70 0.10 70 E -1 0 -1 1 -4 2 6 -3 0 -4 -3 1 -2 -4 -1 0 -1 -3 -2 -3 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0.89 0.10 71 A 4 -2 2 -1 -1 -1 -1 0 -1 -2 -2 -1 -1 -3 -1 1 0 -3 -2 -1 83 0 17 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.42 0.08 72 N -1 -1 5 1 -3 0 2 -1 0 -3 -3 0 -2 -3 -2 1 1 -4 -2 -3 0 0 65 0 0 0 18 0 0 0 0 0 0 0 0 6 11 0 0 0 0.58 0.09 73 I -2 2 -2 -3 -2 0 -2 -3 -2 3 2 -1 3 -1 -3 -2 -1 -2 -2 1 0 18 0 0 0 5 0 0 0 33 24 0 20 0 0 0 0 0 0 0 0.26 0.09 74 Y -2 -2 2 -2 -3 -1 -2 -3 1 -2 -2 -2 -1 2 -3 -1 -2 1 7 -2 0 0 18 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 82 0 0.81 0.09 75 A 4 -2 -2 -2 -1 -1 -1 0 -2 -2 -2 -1 -1 -3 -1 1 1 -3 -2 0 86 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 14 0 0 0 0.46 0.09 76 A 3 -1 -1 -2 -1 2 -1 2 -2 -1 -1 -1 1 -2 -2 0 -1 -3 -2 1 50 0 0 0 0 19 0 14 0 0 0 0 6 0 0 0 0 0 0 12 0.25 0.09 77 K -1 4 -1 -1 -4 1 0 -2 -1 -3 -3 5 -2 -3 -2 -1 -1 -3 -2 -3 0 30 0 0 0 0 0 0 0 0 0 70 0 0 0 0 0 0 0 0 0.64 0.09 78 T -1 -1 1 -1 5 -1 -1 -2 -2 -1 -2 0 -1 -3 -2 1 4 -3 -2 -1 0 0 6 0 20 0 0 0 0 0 0 7 0 0 0 0 67 0 0 0 0.46 0.09 79 A 4 -2 -2 -2 -1 -1 -1 1 -2 -2 -2 -1 -1 -3 -1 1 0 -3 -2 -1 84 0 0 0 0 0 0 8 0 0 0 0 0 0 0 8 0 0 0 0 0.47 0.09 80 V 1 -2 -3 -3 -1 -2 -2 -2 -3 2 1 -2 1 -1 -2 -1 0 -3 -1 4 20 0 0 0 0 0 0 0 0 0 11 0 0 0 0 0 0 0 0 69 0.28 0.05 81 T 0 -1 2 1 -2 -1 -1 3 -1 -3 -3 -1 -2 -3 -2 2 2 -3 -2 -2 0 0 11 11 0 0 0 24 0 0 0 0 0 0 0 34 20 0 0 0 0.35 0.04 82 A 4 -2 -2 -2 -1 -1 -1 0 -2 -1 -2 -1 -1 -2 -1 1 0 -3 -2 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.45 0.03 K Lambda Standard Ungapped 0.1252 0.3120 Standard Gapped 0.0410 0.2670 PSI Ungapped 0.1461 0.3184 PSI Gapped 0.0447 0.2670